6B92
Crystal Structure of the N-terminal domain of human METTL16 in complex with SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | polymer | 294 | 33617.8 | 1 | UniProt (Q86W50) Pfam (PF05971) | Homo sapiens (Human) | Methyltransferase 10 domain-containing protein,Methyltransferase-like protein 16,N6-adenosine-methyltransferase METTL16 |
| 2 | B, C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | F (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | G (A) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 1 - 291 (UniProt: Q86W50)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33617.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 632.7 | |
| All* | Total formula weight | 34250.5 |
