6B82
Zebra Fish CYP-450 17A1 Mutant Abiraterone Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytochrome P450, family 17, subfamily A, polypeptide 1 | polymer | 509 | 57471.2 | 2 | UniProt (A2ATX9) Pfam (PF00067) UniProt (by SIFTS) (A0A8M1PIC7) | Danio rerio (Zebrafish) | |
| 2 | C, F (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, G (A, B) | Abiraterone | non-polymer | 349.5 | 2 | Chemie (AER) PubChem (18395627) PubChem (176474465) PubChem (21879648) PubChem (176541408) PubChem (44269384) PubChem (44315376) PubChem (132971) PubChem (57519533) PubChem (70870553) PubChem (70982154) PubChem (73707387) PubChem (90143496) PubChem (118618017) PubChem (124918832) PubChem (99565059) PubChem (117808183) PubChem (117809714) PubChem (117852742) PubChem (118617667) PubChem (118618042) PubChem (118691593) PubChem (124385150) PubChem (15251539) PubChem (124918830) PubChem (124918831) PubChem (129009871) PubChem (129448660) PubChem (129460385) PubChem (131632390) PubChem (132239984) PubChem (135292837) PubChem (144862262) PubChem (144878641) PubChem (144987283) PubChem (144987339) PubChem (155688437) | |||
| 4 | E, I, J, K (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) PubChem (175) | |||
| 5 | H (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 519 (UniProt: A2ATX9)
| PDB | External Database | Details |
|---|---|---|
| Met 17 | - | initiating methionine |
| Ala 18 | - | expression tag |
| Lys 19 | - | expression tag |
| Lys 20 | - | expression tag |
| Thr 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Lys 24 | - | expression tag |
| Gly 25 | - | expression tag |
| Lys 26 | - | expression tag |
| Glu 309 | Asp 309 | engineered mutation |
| Thr 321 | Val 321 | engineered mutation |
| Cys 369 | Arg 369 | engineered mutation |
| Met 372 | Leu 372 | engineered mutation |
| Met 407 | Leu 407 | engineered mutation |
| His 520 | - | expression tag |
| His 521 | - | expression tag |
| His 522 | - | expression tag |
| His 523 | - | expression tag |
| His 524 | - | expression tag |
| His 525 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114942.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2203.6 | |
| All* | Total formula weight | 117146.1 |
