6B5B
Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Baculoviral IAP repeat-containing protein 1e | polymer | 1403 | 159874.8 | 1 | UniProt (Q9R016) Pfam (PF00653) Pfam (PF05729) Pfam (PF22524) Pfam (PF17889) In PDB | Mus musculus (Mouse) | Neuronal apoptosis inhibitory protein 5 |
2 | B, C | NLR family CARD domain-containing protein 4 | polymer | 1024 | 116886.0 | 2 | UniProt (Q3UP24) Pfam (PF17889) Pfam (PF00619) Pfam (PF05729) Pfam (PF22524) In PDB | Mus musculus (Mouse) | Caspase recruitment domain-containing protein 12, Ice protease-activating factor, Ipaf |
3 | F | Flagellin | polymer | 566 | 58494.1 | 1 | UniProt (G8UUW9) Pfam (PF00669) Pfam (PF07196) Pfam (PF00700) UniProt (by SIFTS) (Q5ZVV0) In PDB | Legionella pneumophila |
Sequence modifications
F: 2 - 475 (UniProt: G8UUW9)
PDB | External Database | Details |
---|---|---|
Met -90 | - | initiating methionine |
Glu -89 | - | expression tag |
Gln -88 | - | expression tag |
Lys -87 | - | expression tag |
Leu -86 | - | expression tag |
Ile -85 | - | expression tag |
Ser -84 | - | expression tag |
Glu -83 | - | expression tag |
Glu -82 | - | expression tag |
Asp -81 | - | expression tag |
Leu -80 | - | expression tag |
Asn -79 | - | expression tag |
Glu -78 | - | expression tag |
Met -77 | - | expression tag |
Glu -76 | - | expression tag |
Gln -75 | - | expression tag |
Lys -74 | - | expression tag |
Leu -73 | - | expression tag |
Ile -72 | - | expression tag |
Ser -71 | - | expression tag |
Glu -70 | - | expression tag |
Glu -69 | - | expression tag |
Asp -68 | - | expression tag |
Leu -67 | - | expression tag |
Asn -66 | - | expression tag |
Glu -65 | - | expression tag |
Met -64 | - | expression tag |
Glu -63 | - | expression tag |
Gln -62 | - | expression tag |
Lys -61 | - | expression tag |
Leu -60 | - | expression tag |
Ile -59 | - | expression tag |
Ser -58 | - | expression tag |
Glu -57 | - | expression tag |
Glu -56 | - | expression tag |
Asp -55 | - | expression tag |
Leu -54 | - | expression tag |
Asn -53 | - | expression tag |
Glu -52 | - | expression tag |
Met -51 | - | expression tag |
Glu -50 | - | expression tag |
Gln -49 | - | expression tag |
Lys -48 | - | expression tag |
Leu -47 | - | expression tag |
Ile -46 | - | expression tag |
Ser -45 | - | expression tag |
Glu -44 | - | expression tag |
Glu -43 | - | expression tag |
Asp -42 | - | expression tag |
Leu -41 | - | expression tag |
Asn -40 | - | expression tag |
Glu -39 | - | expression tag |
Met -38 | - | expression tag |
Glu -37 | - | expression tag |
Gln -36 | - | expression tag |
Lys -35 | - | expression tag |
Leu -34 | - | expression tag |
Ile -33 | - | expression tag |
Ser -32 | - | expression tag |
Glu -31 | - | expression tag |
Glu -30 | - | expression tag |
Asp -29 | - | expression tag |
Leu -28 | - | expression tag |
Asn -27 | - | expression tag |
Glu -26 | - | expression tag |
Met -25 | - | expression tag |
Glu -24 | - | expression tag |
Ser -23 | - | expression tag |
Leu -22 | - | expression tag |
Gly -21 | - | expression tag |
Asp -20 | - | expression tag |
Leu -19 | - | expression tag |
Thr -18 | - | expression tag |
Met -17 | - | expression tag |
Glu -16 | - | expression tag |
Gln -15 | - | expression tag |
Lys -14 | - | expression tag |
Leu -13 | - | expression tag |
Ile -12 | - | expression tag |
Ser -11 | - | expression tag |
Glu -10 | - | expression tag |
Glu -9 | - | expression tag |
Asp -8 | - | expression tag |
Leu -7 | - | expression tag |
Asn -6 | - | expression tag |
Ser -5 | - | expression tag |
Gly -4 | - | expression tag |
Arg -3 | - | expression tag |
Pro -2 | - | expression tag |
Ala -1 | - | expression tag |
Ala 0 | - | expression tag |
Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 452140.9 | |
All* | Total formula weight | 452140.9 |