6B4J

Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Nucleoporin GLE1	polymer	317	36375.1	2	UniProt (Q53GS7) Pfam (PF07817) In PDB	Homo sapiens (Human)	hGLE1,GLE1-like protein
2	C, D	Nucleoporin like 2	polymer	49	5427.3	2	UniProt (by SIFTS) (O15504) In PDB	Homo sapiens (Human)
3	E, F	ATP-dependent RNA helicase DDX19B	polymer	430	48658.0	2	UniProt (Q9UMR2) Pfam (PF00270) Pfam (PF00271) In PDB	Homo sapiens (Human)	DEAD box RNA helicase DEAD5,DEAD box protein 19B
4	B, E, F	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
5	E, F	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	E, F	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)

Sequence modifications

B, A: 383 - 698 (UniProt: Q53GS7)

PDB	External Database	Details
Met 382	-	initiating methionine

E, F: 54 - 479 (UniProt: Q9UMR2)

PDB	External Database	Details
Gly 50	-	expression tag
Pro 51	-	expression tag
His 52	-	expression tag
Met 53	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	180920.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1630.8
All*	Total formula weight	182551.7

*Water molecules are not included.