6B4J
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, A) | Nucleoporin GLE1 | polymer | 317 | 36375.1 | 2 | UniProt (Q53GS7) Pfam (PF07817) | Homo sapiens (Human) | hGLE1,GLE1-like protein |
| 2 | B, D (C, D) | Nucleoporin like 2 | polymer | 49 | 5427.3 | 2 | UniProt (by SIFTS) (O15504) | Homo sapiens (Human) | |
| 3 | E, F (E, F) | ATP-dependent RNA helicase DDX19B | polymer | 430 | 48658.0 | 2 | UniProt (Q9UMR2) Pfam (PF00270) Pfam (PF00271) | Homo sapiens (Human) | DEAD box RNA helicase DEAD5,DEAD box protein 19B |
| 4 | G, H, I, J, M... (B, E, F) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 5 | K, O (E, F) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | L, P (E, F) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) |
Sequence modifications
B, A: 383 - 698 (UniProt: Q53GS7)
E, F: 54 - 479 (UniProt: Q9UMR2)
| PDB | External Database | Details |
|---|---|---|
| Met 382 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 50 | - | expression tag |
| Pro 51 | - | expression tag |
| His 52 | - | expression tag |
| Met 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 180920.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1630.8 | |
| All* | Total formula weight | 182551.7 |
