6B0T

Structural Insights into the Induced-fit Inhibition of Fascin by a Small Molecule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Fascin	polymer	487	54026.2	6	UniProt (Q16658) Pfam (PF06268)	Homo sapiens (Human)	55 kDa actin-bundling protein,Singed-like protein,p55
2	G, H, I, J, K... (A, B, C, D, E...)	4-methyl-N-(1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indazol-3-yl)-1,2-oxazole-5-carboxamide	non-polymer		400.4	6	Chemie (C7V)
3	M, N, O, P, Q... (A, B, C, D, E...)	water	water		18.0	344	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	324157.5
Non-Polymers*	Number of molecules	6
	Total formula weight	2402.1
All*	Total formula weight	326559.6

*Water molecules are not included.