6B0F
ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen receptor | polymer | 254 | 28897.9 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (Human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | C, F (A, B) | LSZ102 | non-polymer | 470.5 | 2 | Chemie (C6V) | |||
| 3 | D, E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B: 301 - 553 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Gly 300 | - | expression tag |
| Ser 381 | Cys 381 | engineered mutation |
| Ser 417 | Cys 417 | engineered mutation |
| Ser 530 | Cys 530 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57795.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1217.2 | |
| All* | Total formula weight | 59013.0 |
