6B0F
ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue C6V A 601 |
| Chain | Residue |
| A | LEU346 |
| A | PHE425 |
| A | LEU428 |
| A | GLY521 |
| A | HIS524 |
| A | LEU525 |
| A | TYR526 |
| A | LYS531 |
| A | ASN532 |
| A | VAL533 |
| A | THR347 |
| A | LEU349 |
| A | GLU353 |
| A | LEU387 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | ILE424 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | GLU323 |
| A | PRO325 |
| A | ARG394 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | GLN441 |
| A | GLU444 |
| A | ALA493 |
| A | ARG503 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue C6V B 601 |
| Chain | Residue |
| B | MET343 |
| B | LEU346 |
| B | THR347 |
| B | GLU353 |
| B | LEU387 |
| B | ARG394 |
| B | PHE404 |
| B | ILE424 |
| B | PHE425 |
| B | LEU428 |
| B | GLY521 |
| B | HIS524 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| A | LEU327 |
| A | ARG352 |
| A | HIS356 |
| B | LEU327 |
| B | TYR328 |
| B | ARG352 |
| B | HIS356 |
| B | HOH702 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9338790","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9600906","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A52","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ERE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by Tyr-kinases","evidences":[{"source":"PubMed","id":"7539106","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
