6APT

Trypanosoma brucei hypoxanthine guanine phosphoribosyltransferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hypoxanthine-guanine phosphoribosyltransferase	polymer	216	24221.8	2	UniProt (Q07010) Pfam (PF00156)	Trypanosoma brucei brucei	HGPRTase
2	C, E (A, B)	{[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid)	non-polymer		441.3	2	Chemie (45T)
3	D, F (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
4	G, H (A, B)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

A, B: 1 - 210 (UniProt: Q07010)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48443.6
Non-Polymers*	Number of molecules	4
	Total formula weight	1094.8
All*	Total formula weight	49538.3

*Water molecules are not included.