6APB

Crystal Structure of Non-Neutralizing Infant Antibody ADI-14359 in Complex with Postfusion RSV F Glycoprotein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Fusion glycoprotein F0,Fusion glycoprotein F0	polymer	510	56758.9	3	UniProt (Q84850) UniProt (A0A1P8J9V4) Pfam (PF00523) UniProt (by SIFTS) (P03420)	Human respiratory syncytial virus
2	D (H)	IgG H chain	polymer	230	24824.9	1		Homo sapiens (Human)
3	E (L)	ADI-14359 Fab Light Chain	polymer	214	23278.7	1		Homo sapiens (Human)
4	F, G, H (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 146 (UniProt: Q84850)
A, B, C: 147 - 513 (UniProt: A0A1P8J9V4)

PDB	External Database	Details
Gly 514	-	expression tag
Leu 515	-	expression tag
Glu 516	-	expression tag
Val 517	-	expression tag
Leu 518	-	expression tag
Phe 519	-	expression tag
Gln 520	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	218380.4
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	219044.0

*Water molecules are not included.