6AMB
Crystal Structure of the Afadin RA1 domain in complex with HRAS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTPase HRas | polymer | 170 | 19386.9 | 1 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (Human) | H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras |
| 2 | B (B) | Afadin | polymer | 99 | 11529.0 | 1 | UniProt (Q9QZQ1) Pfam (PF00788) | Mus musculus (Mouse) | Afadin adherens junction formation factor, Protein Af-6 |
| 3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 1 - 168 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30915.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.5 | |
| All* | Total formula weight | 31462.4 |
