6AKG

Crystal structure of mouse claudin-3 P134G mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Claudin-3	polymer	190	19866.4	2	UniProt (Q9Z0G9) Pfam (PF00822) In PDB	Mus musculus (Mouse)
2	B, D	Heat-labile enterotoxin B chain	polymer	119	13329.8	2	UniProt (P01558) In PDB	Clostridium perfringens

Sequence modifications

A, C: 1 - 183 (UniProt: Q9Z0G9)

PDB	External Database	Details
Gly -6	-	see sequence details
His -5	-	see sequence details
Met -4	-	see sequence details
Ala -3	-	see sequence details
Ser -2	-	see sequence details
Gly -1	-	see sequence details
Ser 0	-	see sequence details
Ala 103	Cys 103	engineered mutation
Ala 106	Cys 106	engineered mutation
Gly 134	Pro 134	engineered mutation
Ala 181	Cys 181	engineered mutation
Ala 182	Cys 182	engineered mutation

B, D: 203 - 319 (UniProt: P01558)

PDB	External Database	Details
Gly 201	-	see sequence details
Ser 202	-	see sequence details
Ala 313	Ser 313	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66392.5
All*	Total formula weight	66392.5

*Water molecules are not included.