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6AKG

Crystal structure of mouse claudin-3 P134G mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin

Functional Information from GO Data
ChainGOidnamespacecontents
A0005198molecular_functionstructural molecule activity
A0005923cellular_componentbicellular tight junction
A0016020cellular_componentmembrane
B0005576cellular_componentextracellular region
C0005198molecular_functionstructural molecule activity
C0005923cellular_componentbicellular tight junction
C0016020cellular_componentmembrane
D0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS01346
Number of Residues16
DetailsCLAUDIN Claudin family signature. GLWmnCvvqstgqm.QC
ChainResidueDetails
AGLY48-CYS63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
AMET1-THR8
AGLN102-LYS115
CMET1-THR8
CGLN102-LYS115

site_idSWS_FT_FI2
Number of Residues160
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AGLY9-TRP29
AALA81-ALA101
AILE116-SER136
AGLY160-LEU180
CGLY9-TRP29
CALA81-ALA101
CILE116-SER136
CGLY160-LEU180

site_idSWS_FT_FI3
Number of Residues144
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
AARG30-ARG80
ATRP137-MET159
CARG30-ARG80
CTRP137-MET159

226707

PDB entries from 2024-10-30

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