6AEZ

Crystal structure of human CCL5 trimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	C-C motif chemokine 5	polymer	69	7951.2	2	UniProt (P13501) Pfam (PF00048) In PDB	Homo sapiens (Human)	EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,T-cell-specific protein RANTES
2	B	C-C motif chemokine 5	polymer	69	7993.2	1	UniProt (P13501) Pfam (PF00048) In PDB	Homo sapiens (Human)	EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,T-cell-specific protein RANTES
3	A, B, C	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4		water	water		18.0	194	Chemie (HOH)

Sequence modifications

A, C: 2 - 69 (UniProt: P13501)

PDB	External Database	Details
Met 1	-	initiating methionine
Ser 67	Glu 89	engineered mutation

B: 2 - 69 (UniProt: P13501)

PDB	External Database	Details
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	23895.5
Non-Polymers*	Number of molecules	6
	Total formula weight	576.4
All*	Total formula weight	24471.9

*Water molecules are not included.