6ACI
Crystal structure of EPEC effector NleB in complex with FADD death domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T3SS secreted effector NleB homolog | polymer | 306 | 35105.4 | 1 | UniProt (B7UI21) | Escherichia coli O127:H6 | |
| 2 | B (H) | FAS-associated death domain protein | polymer | 92 | 10614.0 | 1 | UniProt (Q13158) Pfam (PF00531) | Homo sapiens (Human) | FAS-associating death domain-containing protein,Growth-inhibiting gene 3 protein,Mediator of receptor induced toxicity,Protein FADD |
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | E, F (A, H) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence modifications
A: 28 - 329 (UniProt: B7UI21)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ala 115 | Lys 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45719.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 459.1 | |
| All* | Total formula weight | 46178.6 |






