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6ACI

Crystal structure of EPEC effector NleB in complex with FADD death domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
T3SS secreted effector NleB homologpolymer30635105.41UniProt (B7UI21)Escherichia coli O127:H6
2B
(H)
FAS-associated death domain proteinpolymer9210614.01UniProt (Q13158)
Pfam (PF00531)
Homo sapiens (Human)FAS-associating death domain-containing protein,Growth-inhibiting gene 3 protein,Mediator of receptor induced toxicity,Protein FADD
3C
(A)
URIDINE-5'-DIPHOSPHATEnon-polymer404.21Chemie (UDP)
4D
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
5E, F
(A, H)
waterwater18.0436Chemie (HOH)
Sequence modifications
A: 28 - 329 (UniProt: B7UI21)
PDBExternal DatabaseDetails
Ser -3-expression tag
Gly -2-expression tag
Arg -1-expression tag
Pro 0-expression tag
Ala 115Lys 115engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45719.5
Non-Polymers*Number of molecules2
Total formula weight459.1
All*Total formula weight46178.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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