6ACI
Crystal structure of EPEC effector NleB in complex with FADD death domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T3SS secreted effector NleB homolog | polymer | 306 | 35105.4 | 1 | UniProt (B7UI21) Pfam (PF24688) | Escherichia coli O127:H6 | |
| 2 | B (H) | FAS-associated death domain protein | polymer | 92 | 10614.0 | 1 | UniProt (Q13158) Pfam (PF00531) | Homo sapiens (Human) | FAS-associating death domain-containing protein,Growth-inhibiting gene 3 protein,Mediator of receptor induced toxicity,Protein FADD |
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 4 | D (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) PubChem (27854) | |||
| 5 | E, F (A, H) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence modifications
A: 28 - 329 (UniProt: B7UI21)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Arg -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ala 115 | Lys 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45719.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 459.1 | |
| All* | Total formula weight | 46178.6 |
