6A88
Crystal Structure of T. gondii prolyl tRNA synthetase with Febrifugine and ATP Analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Prolyl-tRNA synthetase (ProRS) | polymer | 500 | 57937.3 | 4 | UniProt (S8G8I1) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Toxoplasma gondii ME49 | |
| 2 | A, B, C, D | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 4 | Chemie (ANP) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | A, B, C, D | 3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | non-polymer | 301.3 | 4 | Chemie (9SF) | |||
| 5 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 334 - 830 (UniProt: S8G8I1)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 231749.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3327.4 | |
| All* | Total formula weight | 235076.4 |
