6A88
Crystal Structure of T. gondii prolyl tRNA synthetase with Febrifugine and ATP Analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004827 | molecular_function | proline-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004827 | molecular_function | proline-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004827 | molecular_function | proline-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006433 | biological_process | prolyl-tRNA aminoacylation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004827 | molecular_function | proline-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006433 | biological_process | prolyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ANP A 1001 |
| Chain | Residue |
| A | ARG470 |
| A | ARG594 |
| A | MG1002 |
| A | 9SF1003 |
| A | HOH1117 |
| A | HOH1118 |
| A | HOH1120 |
| A | HOH1121 |
| A | GLU472 |
| A | PHE479 |
| A | LEU480 |
| A | ARG481 |
| A | THR482 |
| A | PHE485 |
| A | GLN555 |
| A | THR592 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | ANP1001 |
| A | HOH1117 |
| A | HOH1118 |
| A | HOH1121 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 9SF A 1003 |
| Chain | Residue |
| A | PHE415 |
| A | THR439 |
| A | GLU441 |
| A | ARG470 |
| A | GLU489 |
| A | HIS491 |
| A | THR558 |
| A | HIS560 |
| A | TRP589 |
| A | GLY590 |
| A | ANP1001 |
| A | HOH1121 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue ANP B 1001 |
| Chain | Residue |
| B | ARG470 |
| B | GLU472 |
| B | PHE479 |
| B | LEU480 |
| B | ARG481 |
| B | THR482 |
| B | PHE485 |
| B | GLN555 |
| B | THR592 |
| B | ARG594 |
| B | MG1002 |
| B | 9SF1003 |
| B | HOH1106 |
| B | HOH1109 |
| B | HOH1115 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | ANP1001 |
| B | HOH1102 |
| B | HOH1106 |
| B | HOH1109 |
| B | HOH1115 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue 9SF B 1003 |
| Chain | Residue |
| B | PHE415 |
| B | GLU418 |
| B | PRO438 |
| B | THR439 |
| B | GLU441 |
| B | ARG470 |
| B | PHE534 |
| B | THR558 |
| B | HIS560 |
| B | ANP1001 |
| B | HOH1102 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue ANP C 1001 |
| Chain | Residue |
| C | ARG470 |
| C | GLU472 |
| C | LYS474 |
| C | LEU480 |
| C | ARG481 |
| C | THR482 |
| C | PHE485 |
| C | GLN555 |
| C | ALA557 |
| C | THR592 |
| C | ARG594 |
| C | MG1002 |
| C | 9SF1003 |
| C | HOH1107 |
| C | HOH1108 |
| C | HOH1116 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 1002 |
| Chain | Residue |
| C | ANP1001 |
| C | HOH1107 |
| C | HOH1108 |
| C | HOH1113 |
| C | HOH1116 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue 9SF C 1003 |
| Chain | Residue |
| C | PHE415 |
| C | PRO438 |
| C | THR439 |
| C | GLU441 |
| C | ARG470 |
| C | HIS491 |
| C | PHE534 |
| C | THR558 |
| C | HIS560 |
| C | TRP589 |
| C | ANP1001 |
| C | HOH1116 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for residue ANP D 1001 |
| Chain | Residue |
| D | LEU480 |
| D | ARG481 |
| D | THR482 |
| D | PHE485 |
| D | GLN555 |
| D | THR592 |
| D | ARG594 |
| D | MG1002 |
| D | 9SF1003 |
| D | HOH1107 |
| D | HOH1115 |
| D | HOH1122 |
| D | HOH1129 |
| D | ARG470 |
| D | GLU472 |
| D | PHE479 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 1002 |
| Chain | Residue |
| D | ANP1001 |
| D | HOH1107 |
| D | HOH1114 |
| D | HOH1115 |
| D | HOH1122 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue 9SF D 1003 |
| Chain | Residue |
| D | PHE415 |
| D | GLU418 |
| D | PRO438 |
| D | THR439 |
| D | GLU441 |
| D | ARG470 |
| D | PHE534 |
| D | THR558 |
| D | HIS560 |
| D | TRP589 |
| D | ANP1001 |
| D | HOH1107 |
