6A4B

Structure of TREX2 in complex with a duplex DNA with 2 nucleotide 3'-overhang

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Three prime repair exonuclease 2	polymer	256	28156.8	6	UniProt (Q9R1A9) Pfam (PF00929)	Mus musculus (Mouse)	3'-5' exonuclease TREX2
2	G, H, I, J, K... (G, H, I, J, K...)	DNA (5'-D(*GP*GP*CP*CP*CP*TP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3')	polymer	18	5474.5	6		Mus musculus
3	M, N, O, P, Q... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	11	Chemie (MG)
4	AA, BA, CA, DA, EA... (D, E, F, G, L...)	water	water		18.0	32	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 236 (UniProt: Q9R1A9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	201788.1
Non-Polymers*	Number of molecules	11
	Total formula weight	267.4
All*	Total formula weight	202055.5

*Water molecules are not included.