6A46

Structure of TREX2 in complex with a nucleotide (dCMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Three prime repair exonuclease 2	polymer	256	28156.8	2	UniProt (Q9R1A9) Pfam (PF00929) In PDB	Mus musculus (Mouse)	3'-5' exonuclease TREX2
2	A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B	2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE	non-polymer		307.2	2	Chemie (DCM)
4	A, B	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
5		water	water		18.0	111	Chemie (HOH)

Sequence modifications

A, B: 1 - 236 (UniProt: Q9R1A9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56313.7
Non-Polymers*	Number of molecules	9
	Total formula weight	831.8
All*	Total formula weight	57145.5

*Water molecules are not included.