5ZXF
The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | E3 ubiquitin-protein ligase Mdm2 | polymer | 87 | 10272.1 | 1 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (Human) | |
| 2 | A | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one | non-polymer | 581.5 | 1 | Chemie (NUT) | |||
| 3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10272.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 581.5 | |
| All* | Total formula weight | 10853.6 |
