5ZQR
Tankyrase-2 in complex with compound 40c
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tankyrase-2 | polymer | 168 | 19150.6 | 1 | UniProt (Q9H2K2) Pfam (PF00644) In PDB | Homo sapiens (Human) | TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein |
| 2 | B | Tankyrase-2 | polymer | 48 | 5364.0 | 1 | UniProt (Q9H2K2) In PDB | Homo sapiens (Human) | TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | 2-[4,6-difluoro-1-(2-hydroxyethyl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl]-5,6,7,8-tetrahydroquinazolin-4(3H)-one | non-polymer | 416.5 | 1 | Chemie (9H9) | |||
| 5 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24514.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 853.1 | |
| All* | Total formula weight | 25367.8 |
