5ZF6

Crystal structure of the dimeric human PNPase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Polyribonucleotide nucleotidyltransferase 1, mitochondrial	polymer	647	70712.7	2	UniProt (Q8TCS8) Pfam (PF01138) Pfam (PF03725) Pfam (PF03726) Pfam (PF00013) In PDB	Homo sapiens (Human)	3'-5' RNA exonuclease OLD35,PNPase old-35,Polynucleotide phosphorylase 1,PNPase 1,Polynucleotide phosphorylase-like protein
2		water	water		18.0	66	Chemie (HOH)

Sequence modifications

A, B: 46 - 669 (UniProt: Q8TCS8)

PDB	External Database	Details
Met 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Ser 33	-	expression tag
Ser 34	-	expression tag
Gly 35	-	expression tag
Leu 36	-	expression tag
Val 37	-	expression tag
Pro 38	-	expression tag
Arg 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag
His 42	-	expression tag
Met 43	-	expression tag
Ala 44	-	expression tag
Ser 45	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	141425.5
All*	Total formula weight	141425.5

*Water molecules are not included.