5ZF6

Crystal structure of the dimeric human PNPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0004654	molecular_function	polyribonucleotide nucleotidyltransferase activity
A	0006396	biological_process	RNA processing
A	0006402	biological_process	mRNA catabolic process
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0004654	molecular_function	polyribonucleotide nucleotidyltransferase activity
B	0006396	biological_process	RNA processing
B	0006402	biological_process	mRNA catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00659
Number of Residues	10
Details	GLYCOSYL_HYDROL_F5 Glycosyl hydrolases family 5 signature. LAVDGVNEPD

Chain	Residue	Details
A	LEU157-ASP166

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8K1R3

Chain	Residue	Details
A	LYS250
B	LYS250

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site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS264
A	LYS285
A	LYS289
B	LYS264
B	LYS285
B	LYS289

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8K1R3

Chain	Residue	Details
A	LYS552
B	LYS552

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