5ZBZ
Crystal structure of the DEAD domain of Human eIF4A with sanguinarine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Eukaryotic initiation factor 4A-I | polymer | 220 | 24926.1 | 1 | UniProt (P60842) Pfam (PF00270) In PDB | Homo sapiens (Human) | eIF4A-I,ATP-dependent RNA helicase eIF4A-1 |
| 2 | A | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium | non-polymer | 332.3 | 1 | Chemie (SAU) | |||
| 3 | A | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 4 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A: 20 - 238 (UniProt: P60842)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24926.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 434.4 | |
| All* | Total formula weight | 25360.5 |
