5Z62
Structure of human cytochrome c oxidase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cytochrome c oxidase subunit 1 | polymer | 513 | 57076.9 | 1 | UniProt (P00395) Pfam (PF00115) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide I |
| 2 | B | Cytochrome c oxidase subunit 2 | polymer | 227 | 25580.9 | 1 | UniProt (P00403) Pfam (PF02790) Pfam (PF00116) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide II |
| 3 | C | Cytochrome c oxidase subunit 3 | polymer | 260 | 29844.5 | 1 | UniProt (P00414) Pfam (PF00510) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide III |
| 4 | D | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | polymer | 144 | 16890.5 | 1 | UniProt (P13073) Pfam (PF02936) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit IV isoform 1,COX IV-1 |
| 5 | E | Cytochrome c oxidase subunit 5A, mitochondrial | polymer | 109 | 12517.1 | 1 | UniProt (P20674) Pfam (PF02284) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide Va |
| 6 | F | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 98 | 10627.0 | 1 | UniProt (P10606) Pfam (PF01215) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide Vb |
| 7 | G | Cytochrome c oxidase subunit 6A1, mitochondrial | polymer | 75 | 8691.9 | 1 | UniProt (P12074) Pfam (PF02046) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide VIa-liver,Cytochrome c oxidase subunit VIA-liver,COX VIa-L |
| 8 | H | Cytochrome c oxidase subunit 6B1 | polymer | 82 | 9757.9 | 1 | UniProt (P14854) Pfam (PF02297) In PDB | Homo sapiens (Human) | Cytochrome c oxidase subunit VIb isoform 1,COX VIb-1 |
| 9 | I | Cytochrome c oxidase subunit 6C | polymer | 73 | 8596.2 | 1 | UniProt (P09669) Pfam (PF02937) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide VIc |
| 10 | J | Cytochrome c oxidase subunit 7A2, mitochondrial | polymer | 56 | 6196.2 | 1 | UniProt (P14406) Pfam (PF02238) In PDB | Homo sapiens (Human) | Cytochrome c oxidase subunit VIIa-liver/heart,Cytochrome c oxidase subunit VIIaL |
| 11 | K | Cytochrome c oxidase subunit 7B, mitochondrial | polymer | 49 | 5488.2 | 1 | UniProt (P24311) Pfam (PF05392) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide VIIb |
| 12 | L | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 47 | 5363.2 | 1 | UniProt (P15954) Pfam (PF02935) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide VIIc |
| 13 | M | Cytochrome c oxidase subunit 8A, mitochondrial | polymer | 43 | 4769.7 | 1 | UniProt (P10176) Pfam (PF02285) In PDB | Homo sapiens (Human) | Cytochrome c oxidase polypeptide VIII-liver/heart,Cytochrome c oxidase subunit 8-2 |
| 14 | N | Cytochrome c oxidase subunit NDUFA4 | polymer | 79 | 9137.5 | 1 | UniProt (O00483) Pfam (PF06522) In PDB | Homo sapiens (Human) | |
| 15 | A, B | COPPER (II) ION | non-polymer | 63.5 | 3 | Chemie (CU) | |||
| 16 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 17 | A | HEME-A | non-polymer | 852.8 | 2 | Chemie (HEA) | |||
| 18 | A, C | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 749.1 | 3 | Chemie (PEE) | |||
| 19 | C | CARDIOLIPIN | non-polymer | 1464.0 | 1 | Chemie (CDL) | |||
| 20 | F | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 210537.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 5697.3 | |
| All* | Total formula weight | 216235.0 |
