5YPN

Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Metallo-beta-lactamase NDM-1	polymer	242	25631.8	2	UniProt (A0A0A7Y424) Pfam (PF00753) UniProt (by SIFTS) (E5KIY2)	Escherichia coli
2	C, D, G, H (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	E, I (A, B)	(2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid	non-polymer		401.5	2	Chemie (LMP)
4	F, J (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	K, L (A, B)	water	water		18.0	176	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51263.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1256.7
All*	Total formula weight	52520.4

*Water molecules are not included.