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5YPN

Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0016787molecular_functionhydrolase activity
A0017001biological_processantibiotic catabolic process
A0046872molecular_functionmetal ion binding
B0016787molecular_functionhydrolase activity
B0017001biological_processantibiotic catabolic process
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 301
ChainResidue
AHIS120
AHIS122
AHIS189
ALMP303

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN A 302
ChainResidue
AASP124
ACYS208
AHIS250
ALMP303

site_idAC3
Number of Residues16
Detailsbinding site for residue LMP A 303
ChainResidue
ATRP93
AHIS120
AHIS122
AGLN123
AASP124
AHIS189
ACYS208
ALYS211
AGLY219
AASN220
AHIS250
AZN301
AZN302
BGLY69
BLMP303
AVAL73

site_idAC4
Number of Residues3
Detailsbinding site for residue SO4 A 304
ChainResidue
AARG234
ATHR260
AARG264

site_idAC5
Number of Residues4
Detailsbinding site for residue ZN B 301
ChainResidue
BHIS120
BHIS122
BHIS189
BLMP303

site_idAC6
Number of Residues4
Detailsbinding site for residue ZN B 302
ChainResidue
BASP124
BCYS208
BHIS250
BLMP303

site_idAC7
Number of Residues16
Detailsbinding site for residue LMP B 303
ChainResidue
AGLY69
APHE70
ALMP303
BTRP93
BHIS120
BHIS122
BGLN123
BASP124
BHIS189
BCYS208
BLYS211
BGLY219
BASN220
BHIS250
BZN301
BZN302

site_idAC8
Number of Residues3
Detailsbinding site for residue SO4 B 304
ChainResidue
AHIS159
ASER160
BHOH418

226707

PDB entries from 2024-10-30

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