5YL4
CRYSTAL STRUCTURE OF T2R-TTL-8WR COMPLEX
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Tubulin alpha chain | polymer | 450 | 50041.3 | 2 | UniProt (A0A0R4I993) Pfam (PF00091) Pfam (PF03953) In PDB | Sus barbatus (Bearded pig) | |
2 | B, D | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (A0A0R4I995) Pfam (PF00091) Pfam (PF03953) In PDB | Sus barbatus (Bearded pig) | |
3 | E | Stathmin-4 | polymer | 143 | 16844.2 | 1 | UniProt (P63043) Pfam (PF00836) In PDB | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
4 | F | Tubulin tyrosine ligase | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) In PDB | Gallus gallus (Chicken) | |
5 | A, C, D | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 3 | Chemie (GTP) | |||
6 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
7 | A, B, C | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
8 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
9 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
10 | B | (3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(phenylcarbonyl)phenyl]methylidene]piperazine-2,5-dione | non-polymer | 440.5 | 1 | Chemie (8WR) | |||
11 | F | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
12 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
E: 5 - 145 (UniProt: P63043)
F: 1 - 378 (UniProt: E1BQ43)
PDB | External Database | Details |
---|---|---|
Met 3 | - | expression tag |
Ala 4 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 379 | - | expression tag |
His 380 | - | expression tag |
His 381 | - | expression tag |
His 382 | - | expression tag |
His 383 | - | expression tag |
His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 261305.0 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3566.4 | |
All* | Total formula weight | 264871.3 |