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5YBF

Crystal structure of the GluA2o LBD in complex with glutamate and HBT1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Glutamate receptor 2,Glutamate receptor 2polymer26329337.86UniProt (P42262)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Homo sapiens (Human)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2A, B, C, D, E...GLUTAMIC ACIDnon-polymer147.16Chemie (GLU)
3A, C, E2-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanoylamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamidenon-polymer386.43Chemie (8SR)
4F, A, B, C, DZINC IONnon-polymer65.410Chemie (ZN)
5C, DACETATE IONnon-polymer59.02Chemie (ACT)
6waterwater18.01653Chemie (HOH)
Sequence modifications
A, B, C, D, E, F: 413 - 527 (UniProt: P42262)
PDBExternal DatabaseDetails
Gly 411-expression tag
Ser 412-expression tag
A, B, C, D, E, F: 653 - 796 (UniProt: P42262)
PDBExternal DatabaseDetails
Gly 641-linker
Thr 642-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight176027.0
Non-Polymers*Number of molecules21
Total formula weight2814.1
All*Total formula weight178841.1
*Water molecules are not included.

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PDB entries from 2024-09-04

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