5Y7X
Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor delta | polymer | 292 | 33319.6 | 2 | UniProt (Q03181) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
2 | A, B | 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid | non-polymer | 500.4 | 2 | Chemie (8RR) | |||
3 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | A | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
6 | A, B | hexyl beta-D-glucopyranoside | non-polymer | 264.3 | 2 | Chemie (JZR) | |||
7 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A, B: 171 - 441 (UniProt: Q03181)
PDB | External Database | Details |
---|---|---|
Met 150 | - | expression tag |
Gly 151 | - | expression tag |
Ser 152 | - | expression tag |
Ser 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
His 156 | - | expression tag |
His 157 | - | expression tag |
His 158 | - | expression tag |
His 159 | - | expression tag |
Ser 160 | - | expression tag |
Ser 161 | - | expression tag |
Gly 162 | - | expression tag |
Leu 163 | - | expression tag |
Val 164 | - | expression tag |
Pro 165 | - | expression tag |
Arg 166 | - | expression tag |
Gly 167 | - | expression tag |
Ser 168 | - | expression tag |
His 169 | - | expression tag |
Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66639.2 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1715.5 | |
All* | Total formula weight | 68354.7 |