5Y7X
Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor delta | polymer | 292 | 33319.6 | 2 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (Human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | C, H (A, B) | 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid | non-polymer | 500.4 | 2 | Chemie (8RR) PubChem (53375028) | |||
| 3 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 4 | E, I (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 5 | F (A) | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
| 6 | G, J (A, B) | hexyl beta-D-glucopyranoside | non-polymer | 264.3 | 2 | Chemie (JZR) PubChem (181215) PubChem (447027) PubChem (4462283) PubChem (11288533) PubChem (12986433) PubChem (14656368) PubChem (17753866) PubChem (25323117) PubChem (26470594) PubChem (67411650) PubChem (67413670) PubChem (69135463) PubChem (171355) PubChem (57031297) PubChem (67409435) PubChem (67410024) PubChem (67410681) PubChem (67410683) PubChem (67411125) PubChem (67412168) PubChem (67412175) PubChem (69572815) PubChem (69647610) PubChem (71317242) PubChem (92223463) PubChem (95162434) PubChem (95162435) PubChem (101527252) PubChem (118908285) PubChem (118908318) PubChem (174070873) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A, B: 171 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Met 150 | - | expression tag |
| Gly 151 | - | expression tag |
| Ser 152 | - | expression tag |
| Ser 153 | - | expression tag |
| His 154 | - | expression tag |
| His 155 | - | expression tag |
| His 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
| His 159 | - | expression tag |
| Ser 160 | - | expression tag |
| Ser 161 | - | expression tag |
| Gly 162 | - | expression tag |
| Leu 163 | - | expression tag |
| Val 164 | - | expression tag |
| Pro 165 | - | expression tag |
| Arg 166 | - | expression tag |
| Gly 167 | - | expression tag |
| Ser 168 | - | expression tag |
| His 169 | - | expression tag |
| Met 170 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66639.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1715.5 | |
| All* | Total formula weight | 68354.7 |
