5Y4H
Human SIRT3 in complex with halistanol sulfate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | polymer | 285 | 31612.3 | 1 | UniProt (Q9NTG7) Pfam (PF02146) In PDB | Homo sapiens (Human) | hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3 |
| 2 | B | THr-Arg-Ser-GLY-ALY-VAL-MET-ARG-ARG-LEU-ARG-ARG | polymer | 12 | 1562.9 | 1 | UniProt (by SIFTS) (Q9NUB1) In PDB | Homo sapiens | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | [(2~{S},3~{S},5~{S},6~{S},8~{S},9~{S},10~{R},13~{R},14~{R},17~{R})-17-[(2~{R})-6,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3-disulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-6-yl] hydrogen sulfate | non-polymer | 674.9 | 1 | Chemie (8QF) | |||
| 5 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A: 118 - 399 (UniProt: Q9NTG7)
| PDB | External Database | Details |
|---|---|---|
| Ser 115 | - | expression tag |
| Asn 116 | - | expression tag |
| Ala 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33175.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 740.3 | |
| All* | Total formula weight | 33915.6 |
