5XVE

Crystal structure of human USP2 C276S mutant in complex with ubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ubiquitin carboxyl-terminal hydrolase 2	polymer	356	41193.6	1	UniProt (O75604) Pfam (PF00443) In PDB	Homo sapiens (Human)	41 kDa ubiquitin-specific protease,Deubiquitinating enzyme 2,Ubiquitin thioesterase 2,Ubiquitin-specific-processing protease 2
2	B	Ubiquitin-40S ribosomal protein S27a	polymer	76	8576.8	1	UniProt (P62992) Pfam (PF00240) In PDB	Bos taurus (Bovine)	Ubiquitin carboxyl extension protein 80
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4		water	water		18.0	356	Chemie (HOH)

Sequence modifications

A: 258 - 605 (UniProt: O75604)

PDB	External Database	Details
Ser 276	Cys 276	conflict
Leu 606	-	expression tag
Glu 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag
His 612	-	expression tag
His 613	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49770.4
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	49835.8

*Water molecules are not included.