5XU8
Crystal structure of human USP2 in complex with ubiquitin and 6-thioguanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin carboxyl-terminal hydrolase 2 | polymer | 356 | 41209.7 | 1 | UniProt (O75604) Pfam (PF00443) | Homo sapiens (Human) | 41 kDa ubiquitin-specific protease,Deubiquitinating enzyme 2,Ubiquitin thioesterase 2,Ubiquitin-specific-processing protease 2 |
| 2 | B (B) | Ubiquitin-40S ribosomal protein S27a | polymer | 76 | 8576.8 | 1 | UniProt (P62992) Pfam (PF00240) | Bos taurus (Bovine) | Ubiquitin carboxyl extension protein 80 |
| 3 | C (A) | 2-amino-1,9-dihydro-6H-purine-6-thione | non-polymer | 167.2 | 1 | Chemie (DX4) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F, L, M, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | G, H, I, J, K (A) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence modifications
A: 258 - 605 (UniProt: O75604)
| PDB | External Database | Details |
|---|---|---|
| Leu 606 | - | expression tag |
| Glu 607 | - | expression tag |
| His 608 | - | expression tag |
| His 609 | - | expression tag |
| His 610 | - | expression tag |
| His 611 | - | expression tag |
| His 612 | - | expression tag |
| His 613 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49786.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 524.8 | |
| All* | Total formula weight | 50311.3 |
