5XTZ

Crystal structure of GAS41 YEATS bound to H3K27ac peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	YEATS domain-containing protein 4	polymer	163	18800.6	4	UniProt (O95619) Pfam (PF03366)	Homo sapiens (Human)	Glioma-amplified sequence 41,Gas41,NuMA-binding protein 1,NuBI1
2	E (E)	THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA	polymer	10	1044.2	1	UniProt (by SIFTS) (P68431)	Homo sapiens
3	F, G (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	H, I, J, K, L (A, B, C, D, E)	water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, B, C, D: 15 - 159 (UniProt: O95619)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ala 1	-	expression tag
Ser 2	-	expression tag
Met 3	-	expression tag
Thr 4	-	expression tag
Gly 5	-	expression tag
Gly 6	-	expression tag
Gln 7	-	expression tag
Gln 8	-	expression tag
Met 9	-	expression tag
Gly 10	-	expression tag
Arg 11	-	expression tag
Gly 12	-	expression tag
Ser 13	-	expression tag
Gly 14	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	76246.7
Non-Polymers*	Number of molecules	2
	Total formula weight	118.1
All*	Total formula weight	76364.8

*Water molecules are not included.