5XTZ
Crystal structure of GAS41 YEATS bound to H3K27ac peptide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | SER123 |
| A | ASN126 |
| B | GLU87 |
| B | HOH203 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 202 |
| Chain | Residue |
| A | PHE121 |
| A | GLN122 |
| A | SER123 |
| A | ASN126 |
| A | HOH313 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide ARG E 26 and ALY E 27 |
| Chain | Residue |
| A | HIS71 |
| A | SER73 |
| A | TYR74 |
| A | GLY92 |
| A | TRP93 |
| A | GLY94 |
| A | GLU95 |
| A | PHE96 |
| B | ASP140 |
| E | ALA24 |
| E | ALA25 |
| E | SER28 |
| E | HOH101 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for Di-peptide ALY E 27 and SER E 28 |
| Chain | Residue |
| A | HIS71 |
| A | SER73 |
| A | TYR74 |
| A | GLY92 |
| A | TRP93 |
| A | GLY94 |
| A | GLU95 |
| A | PHE121 |
| B | GLN145 |
| E | ARG26 |
| E | ALA29 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | LYS23 | |
| B | SER73 | |
| C | SER73 | |
| D | SER73 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| E | ARG26 | |
| B | LYS37 | |
| C | LYS37 | |
| D | LYS37 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| E | ALY27 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:15684425, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588 |
| Chain | Residue | Details |
| E | SER28 |
