5XTE

Cryo-EM structure of human respiratory complex III (cytochrome bc1 complex)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, N	Cytochrome b-c1 complex subunit 8	polymer	81	9791.2	2	UniProt (O14949) Pfam (PF02939) In PDB	Homo sapiens (Human)	Complex III subunit 8,Complex III subunit VIII,Ubiquinol-cytochrome c reductase complex 9.5 kDa protein,Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
2	B, O	Cytochrome b-c1 complex subunit Rieske, mitochondrial	polymer	57	5893.8	2	UniProt (P47985) Pfam (PF09165) In PDB	Homo sapiens (Human)	Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
3	C, P	Cytochrome b-c1 complex subunit Rieske, mitochondrial	polymer	196	21645.6	2	UniProt (P47985) Pfam (PF02921) Pfam (PF00355) In PDB	Homo sapiens (Human)	Complex III subunit 5,Cytochrome b-c1 complex subunit 5,Rieske iron-sulfur protein,RISP,Ubiquinol-cytochrome c reductase iron-sulfur subunit
4	D, Q	Cytochrome b-c1 complex subunit 9	polymer	62	7189.3	2	UniProt (Q9UDW1) Pfam (PF05365) In PDB	Homo sapiens (Human)	Complex III subunit 9,Complex III subunit X,Cytochrome c1 non-heme 7 kDa protein,Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
5	E, R	Cytochrome b-c1 complex subunit 6, mitochondrial	polymer	75	8990.9	2	UniProt (P07919) Pfam (PF02320) In PDB	Homo sapiens (Human)	Complex III subunit 6,Complex III subunit VIII,Cytochrome c1 non-heme 11 kDa protein,Mitochondrial hinge protein,Ubiquinol-cytochrome c reductase complex 11 kDa protein
6	F, S	Cytochrome b-c1 complex subunit 7	polymer	106	13037.8	2	UniProt (P14927) Pfam (PF02271) In PDB	Homo sapiens (Human)	Complex III subunit 7,Complex III subunit VII,QP-C,Ubiquinol-cytochrome c reductase complex 14 kDa protein
7	G, T	Cytochrome b-c1 complex subunit 10	polymer	51	5958.9	2	UniProt (O14957) Pfam (PF08997) In PDB	Homo sapiens (Human)	Complex III subunit 10,Complex III subunit XI,Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
8	H, U	Cytochrome c1, heme protein, mitochondrial	polymer	241	27388.4	2	UniProt (P08574) Pfam (PF02167) In PDB	Homo sapiens (Human)	Complex III subunit 4,Complex III subunit IV,Cytochrome b-c1 complex subunit 4,Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit,Cytochrome c-1
9	J, V	Cytochrome b	polymer	378	42543.0	2	UniProt (P00156) Pfam (PF00033) Pfam (PF00032) In PDB	Homo sapiens (Human)	Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
10	K, W	Cytochrome b-c1 complex subunit 2, mitochondrial	polymer	419	44946.6	2	UniProt (P22695) Pfam (PF00675) Pfam (PF05193) In PDB	Homo sapiens (Human)	Complex III subunit 2,Core protein II,Ubiquinol-cytochrome-c reductase complex core protein 2
11	L, Y	Cytochrome b-c1 complex subunit 1, mitochondrial	polymer	446	49181.4	2	UniProt (P31930) Pfam (PF00675) Pfam (PF05193) In PDB	Homo sapiens (Human)	Complex III subunit 1,Core protein I,Ubiquinol-cytochrome-c reductase complex core protein 1
12	H, J, L, N, U...	CARDIOLIPIN	non-polymer		1464.0	9	Chemie (CDL)
13	P, C	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
14	J, L, U, V, Y...	1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	non-polymer		749.1	6	Chemie (PEE)
15	H, U	HEME C	non-polymer		618.5	2	Chemie (HEC)
16	J, V	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
17	L, Q, T	(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL	non-polymer		767.1	3	Chemie (PLX)

Contents of the asymmetric unit

Polymers	Number of chains	22
	Total formula weight	473133.8
Non-Polymers*	Number of molecules	26
	Total formula weight	24026.8
All*	Total formula weight	497160.6

*Water molecules are not included.