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5XPG

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'U7' on the target strand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Uncharacterized proteinpolymer68576727.81UniProt (Q746M7)Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Argonaute
2B
(C)
5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3'polymer216588.31Thermus thermophilus
3C
(G)
5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3'polymer206271.81Thermus thermophilus
4D, E
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6G, H
(A, G)
waterwater18.023Chemie (HOH)
Sequence modifications
A: 1 - 685 (UniProt: Q746M7)
PDBExternal DatabaseDetails
Asn 546Asp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89587.8
Non-Polymers*Number of molecules3
Total formula weight216.4
All*Total formula weight89804.2
*Water molecules are not included.

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PDB entries from 2026-01-14

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