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5XPG

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'U7' on the target strand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AUncharacterized proteinpolymer68576727.81UniProt (Q746M7)
Pfam (PF22472)
Pfam (PF18309)
Pfam (PF22474)
In PDB
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Argonaute
2C5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3'polymer216588.31Thermus thermophilus
3G5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3'polymer206271.81Thermus thermophilus
4ASULFATE IONnon-polymer96.12Chemie (SO4)
5CMAGNESIUM IONnon-polymer24.31Chemie (MG)
6waterwater18.023Chemie (HOH)
Sequence modifications
A: 1 - 685 (UniProt: Q746M7)
PDBExternal DatabaseDetails
Asn 546Asp 546engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight89587.8
Non-Polymers*Number of molecules3
Total formula weight216.4
All*Total formula weight89804.2
*Water molecules are not included.

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PDB entries from 2024-09-11

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