5XIT
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form II
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, F | Ubiquitin-40S ribosomal protein S27a | polymer | 76 | 8604.8 | 2 | UniProt (P62983) Pfam (PF00240) In PDB | Mus musculus (Mouse) | Ubiquitin carboxyl extension protein 80 |
2 | E, A | E3 ubiquitin-protein ligase RNF168 | polymer | 81 | 9618.5 | 2 | UniProt (Q8IYW5) In PDB | Homo sapiens (Human) | hRNF168,RING finger protein 168,RING-type E3 ubiquitin transferase RNF168 |
3 | H, B | Ubiquitin-40S ribosomal protein S27a | polymer | 77 | 8691.9 | 2 | UniProt (P62983) Pfam (PF00240) In PDB | Mus musculus (Mouse) | Ubiquitin carboxyl extension protein 80 |
4 | D, E, A | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | E | PRASEODYMIUM ION | non-polymer | 140.9 | 3 | Chemie (PR) | |||
6 | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
D, F: 1 - 76 (UniProt: P62983)
E, A: 113 - 188 (UniProt: Q8IYW5)
H, B: 1 - 76 (UniProt: P62983)
PDB | External Database | Details |
---|---|---|
Arg 63 | Lys 63 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 108 | - | expression tag |
Pro 109 | - | expression tag |
Gly 110 | - | expression tag |
His 111 | - | expression tag |
Met 112 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Asp 77 | - | see sequence details |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 53830.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 883.2 | |
All* | Total formula weight | 54713.7 |