5XC6

Dengue Virus 4 NS3 Helicase in complex with SSRNA SLA12

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NS3 Helicase	polymer	451	51365.5	2	UniProt (M9P7S0) Pfam (PF07652) Pfam (PF20907) In PDB	Dengue virus 4
2	C, D	RNA (5'-R(*AP*GP*UP*UP*GP*UP*UP*AP*GP*UP*CP*U)-3')	polymer	12	3791.2	2		synthetic construct
3	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)

Sequence modifications

A, B: 172 - 618 (UniProt: M9P7S0)

PDB	External Database	Details
Gly 168	-	expression tag
Ser 169	-	expression tag
Ala 170	-	expression tag
Met 171	-	expression tag
Asp 250	Glu 1724	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110313.6
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	110503.5

*Water molecules are not included.