5X74
The crystal Structure PDE delta in complex with compound (R, R)-1g
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 150 | 17399.0 | 1 | UniProt (O43924) Pfam (PF05351) In PDB | Homo sapiens (Human) | GMP-PDE delta,Protein p17 |
| 2 | A | (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one | non-polymer | 593.7 | 1 | Chemie (JAY) | |||
| 3 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 1 - 150 (UniProt: O43924)
| PDB | External Database | Details |
|---|---|---|
| Ser 110 | Glu 110 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17399.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 593.7 | |
| All* | Total formula weight | 17992.6 |
