5WZ2
Crystal structure of Zika virus NS5 methyltransferase bound to SAM and RNA analogue (m7GpppA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | NS5 MTase | polymer | 276 | 30691.0 | 3 | UniProt (A0A140E7U5) Pfam (PF01728) UniProt (by SIFTS) (A0A109PRQ3) | Zika virus (strain Mr 766) (ZIKV) | Genome polyprotein |
| 2 | D, F, H (A, B, C) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 3 | Chemie (SAM) | |||
| 3 | E, G, I (A, B, C) | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 3 | Chemie (GTA) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B, C: 7 - 276 (UniProt: A0A140E7U5)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 92073.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3557.6 | |
| All* | Total formula weight | 95630.6 |
