5WPL
KRas G12V, bound to GppNHp and miniprotein 225-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | GTPase HRas | polymer | 166 | 18960.4 | 4 | UniProt (P01112) Pfam (PF00071) | Homo sapiens (Human) | H-Ras-1,Ha-Ras,Transforming protein p21,c-H-ras,p21ras |
| 2 | B, C, E, F, H... (B, C, E, F, H...) | Ras-binding peptide | polymer | 32 | 3796.2 | 8 | Saccharomyces cerevisiae | ||
| 3 | M, R, U, Y (A, D, G, J) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
| 4 | N, S, V, W, Z (A, D, G, J) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 5 | AA, BA, CA, O, P... (J, L, A, D, G) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 1 - 166 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | variant |
| Pro 121 | Ala 121 | conflict |
| Ser 122 | Ala 122 | conflict |
| Lys 165 | Gln 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 106211.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2530.9 | |
| All* | Total formula weight | 108742.1 |
