5WHE
KRas G12V/D38P, bound to GppNHp and miniprotein 225-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, G, J) | GTPase KRas | polymer | 170 | 19136.6 | 4 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | E, F, G, H, I... (B, C, E, F, H...) | Miniprotein 225-11 | polymer | 35 | 3997.4 | 8 | synthetic construct | ||
| 3 | AA, M, S, W (J, A, D, G) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
| 4 | CA, DA, N, O, P... (F, A, D, G) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 5 | BA, R, V, Z (J, A, D, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | EA, FA, GA, HA, IA... (A, D, G, J, B...) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
| Pro 38 | Asp 38 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 108525.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2586.8 | |
| All* | Total formula weight | 111112.3 |
