5WGK
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with HPB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Hdac6 protein | polymer | 364 | 40285.5 | 1 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) In PDB | Danio rerio (Zebrafish) | histone deacetylase 6 |
| 2 | A | IODIDE ION | non-polymer | 126.9 | 11 | Chemie (IOD) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 5 | A | N-hydroxy-4-{[(2-hydroxyethyl)(phenylacetyl)amino]methyl}benzamide | non-polymer | 328.4 | 1 | Chemie (AGJ) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
| 7 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: A7YT55)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40285.5 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 2882.1 | |
| All* | Total formula weight | 43167.6 |
