5WBU
Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Serine/threonine-protein kinase mTOR | polymer | 1177 | 134865.5 | 2 | UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) In PDB | Homo sapiens (Human) | FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1 |
2 | D, C | Target of rapamycin complex subunit LST8 | polymer | 328 | 36054.2 | 2 | UniProt (Q9BVC4) Pfam (PF00400) In PDB | Homo sapiens (Human) | TORC subunit LST8,G protein beta subunit-like,Protein GbetaL,Mammalian lethal with SEC13 protein 8,mLST8 |
3 | P, R, O, Q | Proline-rich AKT1 substrate 1 | polymer | 88 | 9848.0 | 4 | UniProt (Q96B36) Pfam (PF15798) In PDB | Homo sapiens (Human) | 40 kDa proline-rich AKT substrate |
Sequence modifications
B, A: 1376 - 2549 (UniProt: P42345)
D, C: 1 - 326 (UniProt: Q9BVC4)
P, R, O, Q: 173 - 256 (UniProt: Q96B36)
PDB | External Database | Details |
---|---|---|
Gly 1373 | - | expression tag |
Thr 1374 | - | expression tag |
Gly 1375 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 169 | - | expression tag |
Ser 170 | - | expression tag |
Gly 171 | - | expression tag |
Arg 172 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 381231.5 | |
All* | Total formula weight | 381231.5 |