5W5K
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with KV70
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Histone deacetylase 6 | polymer | 364 | 40285.5 | 3 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) In PDB | Danio rerio (Zebrafish) | Hdac6 protein |
| 2 | A, B, C | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | A, B, C | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 4 | A, B, C | 10-{[4-(hydroxycarbamoyl)phenyl]methyl}-5lambda~4~-pyrido[3,2-b][1,4]benzothiazin-10-ium | non-polymer | 350.4 | 3 | Chemie (K70) | |||
| 5 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A, B, C: 440 - 798 (UniProt: A7YT55)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 120856.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1482.1 | |
| All* | Total formula weight | 122338.5 |
