5W4V
Structure of RORgt bound to a tertiary alcohol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Nuclear receptor ROR-gamma | polymer | 210 | 24508.3 | 6 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | A, B, C, D, E... | (R)-(4-chloro-2-methoxy-3-{[4-(1H-pyrazol-1-yl)phenyl]methyl}quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)[6-(trifluoromethyl)pyridin-3-yl]methanol | non-polymer | 605.0 | 6 | Chemie (9WA) | |||
| 3 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 266 - 475 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| His 455 | Cys 455 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 147050.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3630.1 | |
| All* | Total formula weight | 150680.1 |
