5W4V
Structure of RORgt bound to a tertiary alcohol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| E | 0003677 | molecular_function | DNA binding |
| E | 0004879 | molecular_function | nuclear receptor activity |
| E | 0005634 | cellular_component | nucleus |
| E | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0003677 | molecular_function | DNA binding |
| F | 0004879 | molecular_function | nuclear receptor activity |
| F | 0005634 | cellular_component | nucleus |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 9WA A 501 |
| Chain | Residue |
| A | LEU287 |
| A | PHE388 |
| A | ILE400 |
| A | PHE401 |
| A | CYS320 |
| A | HIS323 |
| A | LEU324 |
| A | MET365 |
| A | PHE377 |
| A | PHE378 |
| A | GLU379 |
| A | GLY380 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 9WA B 501 |
| Chain | Residue |
| A | MET313 |
| A | TRP314 |
| B | CYS320 |
| B | LEU324 |
| B | VAL361 |
| B | MET365 |
| B | PHE377 |
| B | PHE378 |
| B | GLU379 |
| B | GLY380 |
| B | PHE388 |
| B | ILE400 |
| B | PHE401 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 9WA C 501 |
| Chain | Residue |
| C | HIS323 |
| C | LEU324 |
| C | MET365 |
| C | VAL376 |
| C | PHE377 |
| C | PHE378 |
| C | GLU379 |
| C | GLY380 |
| C | PHE388 |
| C | LEU396 |
| C | ILE400 |
| C | PHE401 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue 9WA D 501 |
| Chain | Residue |
| D | LEU287 |
| D | CYS320 |
| D | LEU324 |
| D | VAL361 |
| D | MET365 |
| D | VAL376 |
| D | PHE377 |
| D | PHE378 |
| D | GLU379 |
| D | GLY380 |
| D | PHE388 |
| D | ILE400 |
| D | PHE401 |
| E | TRP314 |
| E | TRP317 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue 9WA E 501 |
| Chain | Residue |
| D | TRP314 |
| E | CYS320 |
| E | HIS323 |
| E | LEU324 |
| E | MET365 |
| E | PHE377 |
| E | GLU379 |
| E | GLY380 |
| E | PHE388 |
| E | PHE401 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue 9WA F 501 |
| Chain | Residue |
| C | MET313 |
| C | TRP314 |
| F | LEU287 |
| F | CYS320 |
| F | HIS323 |
| F | LEU324 |
| F | LEU362 |
| F | MET365 |
| F | PHE377 |
| F | PHE378 |
| F | GLU379 |
| F | GLY380 |
| F | PHE388 |
| F | ILE400 |
| F | PHE401 |
