5VXZ
High-affinity AXL decoy receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Growth arrest-specific protein 6 | polymer | 395 | 43871.3 | 2 | UniProt (Q14393) Pfam (PF00054) Pfam (PF02210) | Homo sapiens (Human) | GAS-6,AXL receptor tyrosine kinase ligand |
| 2 | C, D (C, D) | Tyrosine-protein kinase receptor UFO | polymer | 102 | 11257.5 | 2 | UniProt (P30530) Pfam (PF13927) | Homo sapiens (Human) | AXL oncogene |
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, I (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | H, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
C, D: 27 - 128 (UniProt: P30530)
| PDB | External Database | Details |
|---|---|---|
| Ser 32 | Gly 39 | engineered mutation |
| Val 72 | Ala 79 | engineered mutation |
| Gly 87 | Asp 94 | engineered mutation |
| Ala 92 | Val 99 | engineered mutation |
| Arg 127 | Gly 134 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110257.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 151.1 | |
| All* | Total formula weight | 111257.5 |
