5VSD
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase EHMT1 | polymer | 261 | 30232.4 | 2 | UniProt (Q9H9B1) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (Human) | Euchromatic histone-lysine N-methyltransferase 1,Eu-HMTase1,G9a-like protein 1,GLP1,Histone H3-K9 methyltransferase 5,H3-K9-HMTase 5,Lysine N-methyltransferase 1D |
| 2 | C, J (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 3 | D, E, F, G, K... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | H, O (A, B) | 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine | non-polymer | 373.5 | 2 | Chemie (9HJ) | |||
| 5 | I (A) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 1 | Chemie (DIO) | |||
| 6 | P, Q (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 529 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60464.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2339.4 | |
| All* | Total formula weight | 62804.2 |
