5VSC
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase EHMT2 | polymer | 275 | 31733.0 | 2 | UniProt (Q96KQ7) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (Human) | Euchromatic histone-lysine N-methyltransferase 2,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3,H3-K9-HMTase 3,Lysine N-methyltransferase 1C,Protein G9a |
| 2 | C, D, E, F, I... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | G, M (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 4 | H, N (A, B) | 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine | non-polymer | 373.5 | 2 | Chemie (9HJ) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63466.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2067.1 | |
| All* | Total formula weight | 65533.1 |
